Comparison of LAI reactivity in B 77 tumor bearing rats between, before and after surgical removal of tumors.

Using a new modification of the tube LAI test, LAI reactivity was followed in rats of the inbred Lewis (LW) strain with transplanted syngeneic B 77 tumors before and one month after a surgical removal of the tumors. A significant decline in LAI reactivity was noted after a thorough extirpation of the tumors as compared to that prior to the surgical intervention. The results have been compared and are here discussed with a view to a possible application of the LAI test in studies of antitumor immunity in patients with a malignant disease.