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质粒ColE1的序列特异性重组

Sequence-specific recombination of plasmid ColE1.

作者信息

Warren G J, Clark A J

出版信息

Proc Natl Acad Sci U S A. 1980 Nov;77(11):6724-8. doi: 10.1073/pnas.77.11.6724.

Abstract

The conjugal transmission of plasmid ColE1 and its derivatives can lead to recA-independent recombination. The recombination is not observed during vegetative growth and takes place specifically between the sequences that are thought to represent the transfer origin of ColE1. This provides genetic evidence for breakage and reunion events during the transmission of ColE1.

摘要

质粒ColE1及其衍生物的接合转移可导致不依赖recA的重组。在营养生长期间未观察到这种重组,且其特异性地发生在被认为代表ColE1转移起点的序列之间。这为ColE1转移过程中的断裂和重连事件提供了遗传学证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5628/350361/26b3a844b3d1/pnas00498-0478-a.jpg

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