Robinson J O, Rosen M, Evans J M, Revill S I, David H, Rees G A
Anaesthesia. 1980 Dec;35(12):1173-81. doi: 10.1111/j.1365-2044.1980.tb05074.x.
In a randomised controlled trial epidural analgesia with bupivacaine 0.5% (mean dose 112.8 mg) was compared with pethidine (mean dose 200 mg) and inhalational analgesia in primipara (28 and 30 mothers) and multipara (17 and 18 mothers). Mothers who had an uneventful pregnancy and labour and agreed to have either treatment were studied during labour and followed-up at interviews for 5 months after delivery. Epidural block was rated significantly superior in respect of pain relief and comfort, there were no differences between the groups in reports of perineal discomfort. Twice as many primipara required forceps delivery after epidural block. Very few mothers, in each group, reported something missing in their experience of childbirth. Two thirds of each group would use the same method again. Epidural block can therefore be recommended to uncommitted mothers as a satisfying and effective method of pain relief for labour.
在一项随机对照试验中,对初产妇(分别为28名和30名母亲)和经产妇(分别为17名和18名母亲)使用0.5%布比卡因(平均剂量112.8毫克)进行硬膜外镇痛,并与哌替啶(平均剂量200毫克)及吸入性镇痛进行比较。选择妊娠和分娩过程顺利且同意接受任何一种治疗的母亲,在分娩期间进行研究,并在产后随访5个月进行访谈。硬膜外阻滞在缓解疼痛和舒适度方面被评定为明显更优,各组间会阴不适报告无差异。硬膜外阻滞后初产妇需要产钳助产的人数是对照组的两倍。每组中很少有母亲表示分娩体验有所欠缺。每组中有三分之二的母亲会再次选择相同的方法。因此,对于尚未做出决定的母亲,硬膜外阻滞可作为一种令人满意且有效的分娩镇痛方法予以推荐。