用蛋白A空斑试验检测到的自发分泌抗体的人血淋巴细胞。
Spontaneous antibody-secreting human blood lymphocytes detected with a protein A plaque assay.
作者信息
Kunori T, Broman P, Tan M
出版信息
Clin Exp Immunol. 1980 Oct;42(1):162-6.
Abstract
Spontaneous antibody-secreting lymphocytes in human peripheral blood were detected and counted by a protein A plaque assay. The level of plaque-forming cells (PFC) in peripheral blood was significantly higher in patients with immune disorders (per 10(6) lymphocytes: IgG PFC, 2,654 +/- 684; IgA PFC, 1,727 +/- 327; IgM PFC, 403 +/- 92) than in normal controls (per 10(6) lymphocytes: IgG PFC, 327 +/- 56; IgA PFC 633 +/- 128; IgM PFC, 215 +/- 105). There was no direct correlation between the PFC numbers of different Ig classes.
摘要
采用蛋白A斑片试验检测并计数人外周血中自发分泌抗体的淋巴细胞。免疫紊乱患者外周血中斑形成细胞（PFC）水平显著高于正常对照（每10⁶淋巴细胞：IgG PFC，2654±684；IgA PFC，1727±327；IgM PFC，403±92）（每10⁶淋巴细胞：IgG PFC，327±56；IgA PFC 633±128；IgM PFC，215±105）。不同Ig类别的PFC数量之间无直接相关性。
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本文引用的文献
1
Lymphoid cellular responses in the blood after immunization in man.人体免疫后血液中的淋巴细胞反应。
J Exp Med. 1969 May 1;129(5):849-69. doi: 10.1084/jem.129.5.849.
2
The atypical lymphocyte.异型淋巴细胞。
Am J Med. 1967 Jun;42(6):923-36. doi: 10.1016/0002-9343(67)90073-3.
3
A plaque assay for all cells secreting Ig of a given type or class.针对所有分泌特定类型或类别的免疫球蛋白的细胞进行的噬斑测定。
Eur J Immunol. 1976 Aug;6(8):588-90. doi: 10.1002/eji.1830060812.
4
Activation of human B lymphocytes. I. Direct plaque-forming cell assay for the measurement of polyclonal activation and antigenic stimulation of human B lymphocytes.人类B淋巴细胞的激活。I. 用于测量人类B淋巴细胞多克隆激活和抗原刺激的直接空斑形成细胞测定法。
J Exp Med. 1976 Sep 1;144(3):674-84. doi: 10.1084/jem.144.3.674.
5
Induction of antibody synthesis in human B lymphocytes by different polyclonal B cell activators: evaluation by direct and indirect PFC assays.不同多克隆B细胞激活剂对人B淋巴细胞抗体合成的诱导作用：通过直接和间接空斑形成细胞试验进行评估
Immunol Rev. 1979;45:195-218. doi: 10.1111/j.1600-065x.1979.tb00278.x.
6
Optimal conditions for polyclonal antibody secretion and DNA synthesis in human blood and spleen lymphocytes by lipopolysaccharide.脂多糖诱导人血及脾淋巴细胞分泌多克隆抗体和进行DNA合成的最佳条件。
Scand J Immunol. 1978;8(5):451-8. doi: 10.1111/j.1365-3083.1978.tb00541.x.
7
Polyclonal antibody secretion in human lymphocytes induced by killed staphylococcal bacteria and by lipopolysaccharide.由灭活葡萄球菌和脂多糖诱导的人淋巴细胞中的多克隆抗体分泌。
Scand J Immunol. 1977;6(11):1159-69. doi: 10.1111/j.1365-3083.1977.tb00355.x.
8
The use of bacteria for the functional characterization of human lymphocyte subpopulations in various lymphoid organs.
Scand J Immunol. 1978;8(5):369-75. doi: 10.1111/j.1365-3083.1978.tb00531.x.
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