• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

福氏志贺菌6型核心区域的结构研究

Structural studies on Shigella flexneri serotype 6 core region.

作者信息

Katzenellenbogen E, Romanowska E

出版信息

Eur J Biochem. 1980 Dec;113(1):205-11. doi: 10.1111/j.1432-1033.1980.tb06157.x.

DOI:10.1111/j.1432-1033.1980.tb06157.x
PMID:7007048
Abstract

The core structure of Shigella flexneri serotype 6 has been investigated. The methods used in these studies involved methylation analysis, periodate oxidation, Smith degradation and enzymic modifications of core oligosaccharides isolated from two smooth strains and four rough mutants. As a result the complete core region was established (Formula: see text) where DGalp = D-galactopyranose, DGlcp = D-glucopyranose, L alpha DHepp = L-glycero-D-mannoheptapyranose, dOclA = 3-deoxy-D-manno-octulosonic, DGlcNp = 2-amino-2-deoxy-D-glucopyranose and P--PEtN = pyrophosphorylethanolamine (partially substituted). In the R mutants examined two types of mutation have been observed: (1) defect in heptose region (lack of D-glucosamine) or (2) defects in hexose region of the core.

摘要

福氏志贺菌6型的核心结构已被研究。这些研究中使用的方法包括甲基化分析、高碘酸盐氧化、史密斯降解以及对从两个光滑菌株和四个粗糙突变体中分离出的核心寡糖进行酶促修饰。结果确定了完整的核心区域(化学式:见正文),其中DGalp = D-吡喃半乳糖,DGlcp = D-吡喃葡萄糖,LαDHepp = L-甘油-D-甘露庚糖,dOclA = 3-脱氧-D-甘露辛酮糖酸,DGlcNp = 2-氨基-2-脱氧-D-吡喃葡萄糖,P--PEtN = 焦磷酸乙醇胺(部分取代)。在所检测的R突变体中观察到两种类型的突变:(1)庚糖区域缺陷(缺乏D-葡萄糖胺)或(2)核心己糖区域缺陷。

相似文献

1
Structural studies on Shigella flexneri serotype 6 core region.福氏志贺菌6型核心区域的结构研究
Eur J Biochem. 1980 Dec;113(1):205-11. doi: 10.1111/j.1432-1033.1980.tb06157.x.
2
The structure of the heptose-3-deoxy-D-mannooctulosonic-acid region in a mutant form of Aeromonas salmonicida lipopolysaccharide.
Eur J Biochem. 1986 Dec 1;161(2):309-13. doi: 10.1111/j.1432-1033.1986.tb10448.x.
3
[Chemotypes of "Shigella flexneri" R mutants and related phage receptors. I. -- Chemical study of the lipopolysaccharides (author's transl)].“福氏志贺菌”R突变体的化学型及相关噬菌体受体。I. —— 脂多糖的化学研究(作者译)
Ann Microbiol (Paris). 1976 Jul;127(1):3-14.
4
Structure of the hexose region of Shigella sonnei phase II lipopolysaccharide with 3-deoxy-D-manno-octulosonic acid as possible immunodeterminant and its relation to Escherichia coli R1 core.
Eur J Biochem. 1978 Jul 17;88(1):267-73. doi: 10.1111/j.1432-1033.1978.tb12447.x.
5
Serological analysis of core oligosaccharides of Shigella flexneri serotype 6 and its R mutants lipopolysaccharides.福氏志贺菌6型及其R突变体脂多糖核心寡糖的血清学分析。
Arch Immunol Ther Exp (Warsz). 1981;29(5):567-72.
6
Structure elucidation of the core regions from Citrobacter O4 and O36 lipopolysaccharides by chemical and enzymatic methods, gas chromatography/mass spectrometry, and NMR spectroscopy at 500 MHz.通过化学和酶法、气相色谱/质谱以及500兆赫的核磁共振光谱法对柠檬酸杆菌O4和O36脂多糖核心区域进行结构解析。
Biochemistry. 1988 May 31;27(11):4153-61. doi: 10.1021/bi00411a038.
7
Structural studies on the glucose-heptose region of the Proteus mirabilis R core.奇异变形杆菌R核心中葡萄糖-庚糖区域的结构研究。
Eur J Biochem. 1980;107(1):31-8. doi: 10.1111/j.1432-1033.1980.tb04620.x.
8
Structural and immunochemical studies of the lipopolysaccharide from a new provisional serotype of Shigella flexneri.来自福氏志贺菌新暂定血清型的脂多糖的结构和免疫化学研究。
Eur J Biochem. 1988 Sep 15;176(2):471-6. doi: 10.1111/j.1432-1033.1988.tb14304.x.
9
Full structural characterization of Shigella flexneri M90T serotype 5 wild-type R-LPS and its delta galU mutant: glycine residue location in the inner core of the lipopolysaccharide.福氏志贺菌M90T血清型5野生型R-LPS及其ΔgalU突变体的全结构表征:脂多糖内核中甘氨酸残基的位置
Glycobiology. 2008 Mar;18(3):260-9. doi: 10.1093/glycob/cwm140. Epub 2008 Jan 3.
10
Structural investigations on the inner core region of lipopolysaccharides from Salmonella minnesota rough mutants.对明尼苏达沙门氏菌粗糙突变体脂多糖内核区域的结构研究。
Biomed Mass Spectrom. 1985 Oct;12(10):602-9. doi: 10.1002/bms.1200121007.

引用本文的文献

1
Distribution of core oligosaccharide types in lipopolysaccharides from Escherichia coli.大肠杆菌脂多糖中核心寡糖类型的分布
Infect Immun. 2000 Mar;68(3):1116-24. doi: 10.1128/IAI.68.3.1116-1124.2000.
2
Evolutionary relationships among pathogenic and nonpathogenic Escherichia coli strains inferred from multilocus enzyme electrophoresis and mdh sequence studies.通过多位点酶电泳和苹果酸脱氢酶序列研究推断致病性和非致病性大肠杆菌菌株之间的进化关系。
Infect Immun. 1997 Jul;65(7):2685-92. doi: 10.1128/iai.65.7.2685-2692.1997.
3
Comparison of conjugates composed of lipopolysaccharide from Shigella flexneri type 2a detoxified by two methods and bound to tetanus toxoid.
由两种方法解毒的2a型福氏志贺氏菌脂多糖与破伤风类毒素结合而成的缀合物的比较。
Infect Immun. 1994 Jan;62(1):210-4. doi: 10.1128/iai.62.1.210-214.1994.
4
Structure of the terminal reducing heptasaccharide of polysaccharide 1 isolated from the Bordetella pertussis endotoxin.从百日咳博德特氏菌内毒素中分离出的多糖1末端还原七糖的结构。
J Bacteriol. 1984 Aug;159(2):611-7. doi: 10.1128/jb.159.2.611-617.1984.
5
Characterization of the Shigella serotype D (S. sonnei) O polysaccharide and the enterobacterial R1 lipopolysaccharide core by use of mouse monoclonal antibodies.利用小鼠单克隆抗体对痢疾志贺氏菌血清型D(宋内志贺氏菌)O多糖和肠杆菌R1脂多糖核心进行表征。
Infect Immun. 1992 Jul;60(7):2741-7. doi: 10.1128/iai.60.7.2741-2747.1992.