Sarthy A, Michaelis S, Beckwith J
J Bacteriol. 1981 Jan;145(1):293-8. doi: 10.1128/jb.145.1.293-298.1981.
We present genetic evidence which demonstrates that the phoA gene is transcribed in the clockwise direction on the Escherichia coli chromosome, in contrast to an earlier proposal. Our conclusion is based on analysis of various genetic fusions between the lac operon and the phoA gene.
我们提供了遗传学证据,证明与之前的观点相反,phoA基因在大肠杆菌染色体上是按顺时针方向转录的。我们的结论基于对lac操纵子和phoA基因之间各种基因融合的分析。