Epstein J B, Pearsall N N, Truelove E L
Oral Surg Oral Med Oral Pathol. 1981 Jan;51(1):32-6. doi: 10.1016/0030-4220(81)90123-7.
A human study of the effects of topical nystatin (Mycostatin) therapy of oral candidiasis showed that effects of treatment were limited to the time in which the drug was used. Two weeks of therapy resulted in significant reduction in number of organisms and marked improvement in signs and symptoms of candidiasis. The condition recurred rapidly following cessation of treatment. No change in specific anticandida antibody in saliva or in adherence of Candida albicans to mucosal epithelium (in vitro) was seen with treatment.
一项关于局部应用制霉菌素（制霉菌素片）治疗口腔念珠菌病效果的人体研究表明，治疗效果仅限于用药期间。两周的治疗使念珠菌数量显著减少，念珠菌病的体征和症状明显改善。治疗停止后病情迅速复发。治疗期间，唾液中特异性抗念珠菌抗体或白色念珠菌对黏膜上皮的黏附性（体外）均未见变化。
