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绒毛膜癌细胞系上HLA抗原表达缺失。

Lack of expression of HLA antigens on choriocarcinoma cell lines.

作者信息

Jones E A, Bodmer W F

出版信息

Tissue Antigens. 1980 Aug;16(2):195-202. doi: 10.1111/j.1399-0039.1980.tb00603.x.

DOI:10.1111/j.1399-0039.1980.tb00603.x
PMID:7008252
Abstract

A panel of monoclonal antibodies against HLA--A, B, C, DRw, beta 2 m and other determinants on human cells has been used in indirect trace binding and absorption assays to determine the distribution of these antigens on choriocarcinoma cell lines. HLA--A, B, C, DRw and beta 2 m were not found on these cell lines, while other human antigens expressed on most human tissues were expressed on all the lines.

摘要

一组针对人细胞上 HLA - A、B、C、DRw、β2m 及其他决定簇的单克隆抗体已用于间接微量结合和吸收试验，以确定这些抗原在绒毛膜癌细胞系上的分布。在这些细胞系上未发现 HLA - A、B、C、DRw 和 β2m，而大多数人体组织上表达的其他人类抗原在所有这些细胞系上均有表达。

相似文献

1
Lack of expression of HLA antigens on choriocarcinoma cell lines.绒毛膜癌细胞系上HLA抗原表达缺失。
Tissue Antigens. 1980 Aug;16(2):195-202. doi: 10.1111/j.1399-0039.1980.tb00603.x.
2
Lack of expression of HLA-ABC antigens in choriocarcinoma and other human tumor cell lines.绒毛膜癌及其他人类肿瘤细胞系中HLA - ABC抗原表达缺失。
Natl Cancer Inst Monogr. 1982;60:175-80.
3
Expression of HLA-A, -B, and -C and beta 2-microglobulin antigens in human choriocarcinoma cell lines.人类绒毛膜癌细胞系中HLA-A、-B、-C及β2-微球蛋白抗原的表达
J Exp Med. 1980 Aug 1;152(2 Pt 2):11s-17s.
4
Expression of HLA class I and class II antigens in human choriocarcinoma cell lines.人绒毛膜癌细胞系中HLA I类和II类抗原的表达
Int J Gynaecol Obstet. 1986 Aug;24(4):301-7. doi: 10.1016/0020-7292(86)90088-3.
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Serological analysis of cell surface antigens in choriocarcinoma cell lines.绒毛膜癌细胞系细胞表面抗原的血清学分析
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6
Evidence for a novel HLA antigen found on human extravillous trophoblast and a choriocarcinoma cell line.在人绒毛外滋养层细胞和一种绒毛膜癌细胞系上发现一种新型人类白细胞抗原的证据。
Immunology. 1986 Dec;59(4):595-601.
7
Limitation of differential expression of HLA-A,B,C antigens on choriocarcinoma cell lines by messenger RNA for HLA heavy chain but not by beta 2-microglobulin.人绒毛膜癌细胞系上HLA - A、B、C抗原差异表达的限制因素是HLA重链的信使核糖核酸，而非β2 -微球蛋白。
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[HLA antigens in choriocarcinoma].[绒毛膜癌中的人类白细胞抗原]
Nihon Sanka Fujinka Gakkai Zasshi. 1984 Jan;36(1):81-4.
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The expression of HLA on two cultured choriocarcinoma cell lines.两种培养的绒毛膜癌细胞系上HLA的表达。
Gan. 1982 Feb;73(1):27-34.
10
Gamma-interferon enhances expression of Class I MHC antigens in the weakly HLA+ human choriocarcinoma cell line BeWo, but does not induce MHC expression in the HLA- choriocarcinoma cell line Jar.γ干扰素可增强弱HLA+人绒毛膜癌细胞系BeWo中I类MHC抗原的表达，但不会诱导HLA-绒毛膜癌细胞系Jar中的MHC表达。
J Immunol. 1985 Oct;135(4):2498-501.

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小鼠白血病病毒诱导的肿瘤细胞上H-2抗原表达的定量变化会影响肿瘤特异性细胞溶解T淋巴细胞的H-2限制模式。
J Exp Med. 1981 Dec 1;154(6):1795-810. doi: 10.1084/jem.154.6.1795.
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K562 cells express human major histocompatibility antigens.
Immunogenetics. 1981;13(4):359-65. doi: 10.1007/BF00364503.
5
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J Exp Med. 1987 Dec 1;166(6):1716-33. doi: 10.1084/jem.166.6.1716.
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Proc Natl Acad Sci U S A. 1986 Nov;83(22):8723-7. doi: 10.1073/pnas.83.22.8723.
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