Urist M R, Dawson E
Clin Orthop Relat Res. 1981 Jan-Feb(154):97-113.
Forty intertransverse process spinal fusions were performed across two to three vertebrae in four cases of fracture-dislocations of the dorsolumbar region and 36 cases of degenerative joint and disk disease, including spinal stenosis and spondylolisthesis of lumbosacral segments. In all cases, arthrodesis was performed with a composite of AAA cortical bone strips and local autologous spongiosa, including lamellar bone chips. The iliac crest was not used as a donor site in any case. The apophyseal joints were erased, packed with autologous bone slivers, and transfixed with AAA bone pegs. In selected cases, AAA cortical bone "H-blocks" were also placed between the spinous process as in a routine posterior lateral arthrodesis. In cases of bilateral total laminectomy for fractures or spinal stenosis, the excised cancellous bone chips were cleaned of soft parts and transplanted across the transverse processes beneath and around the AAA cortical bone implants. In the above-described operations, graded by the Anatomic-Functional Economic (AEF) system, the long-term excellent and good results were: 4/4 in fracture dislocations; 23/28 in degenerative arthritis and spinal stenosis; 5/8 in spondylolisthesis. Overall, there were over 80% excellent and good results; the pseudarthrosis rate was 12%. In a comparable surgical procedure with autologous iliac bone in 58 control cases, reported in the foregoing article in this volume, the minimum pseudarthrosis rate was 8%. Raw band bone, either frozen or freeze-dried, is now either so infrequently considered or unavailable for lumbar spinal operations or unavailable for lumbar spinal operations that further investigations of AAA bone grafts are warranted in a statistically significant number of patients. Although autologous bone is the ideal bone for a graft, the most important incentive for further investigations of AAA bone is the avoidance of complications of excision of massive bone grafts from iliac crests.
对4例胸腰段骨折脱位及36例退行性关节和椎间盘疾病(包括腰骶段椎管狭窄和腰椎滑脱)患者进行了40次经横突间脊柱融合术,融合跨越2至3个椎体。所有病例均采用AAA皮质骨条和局部自体松质骨(包括板层骨碎片)的复合物进行关节融合术。所有病例均未使用髂嵴作为供骨部位。切除关节突关节,填入自体骨碎片,并用AAA骨栓固定。在部分病例中,还像常规后外侧关节融合术一样在棘突间放置AAA皮质骨“H形块”。对于因骨折或椎管狭窄而行双侧全椎板切除术的病例,将切除的松质骨碎片清理软组织后,移植到AAA皮质骨植入物下方和周围的横突间。在上述手术中,根据解剖-功能-经济(AEF)系统分级,长期优良结果为:骨折脱位4/4;退行性关节炎和椎管狭窄23/28;腰椎滑脱5/8。总体而言,优良率超过80%;假关节形成率为12%。在前文中报道的58例采用自体髂骨的对照病例的类似手术中,最低假关节形成率为8%。现在,无论是冷冻还是冻干的生带骨,很少被考虑用于腰椎手术或无法用于腰椎手术,因此有必要对大量患者进行AAA骨移植的进一步研究。尽管自体骨是理想的移植骨,但进一步研究AAA骨的最重要诱因是避免从髂嵴切除大块骨移植的并发症。