Melloni G F, Minoja G M, Scorazzati G, Bauer R, Brusoni B, Ghirardi P
Eur J Clin Pharmacol. 1981 Feb;19(3):177-80. doi: 10.1007/BF00561945.
Two groups of 20 patients with no evidence of cardiovascular, hepatic, renal or gastrointestinal failure were treated orally for five days with placebo or SB 7505 100 mg/day. No change was observed in heart rate or blood pressure. Urine output, the excretion of Na, K and Cl, and creatinine clearance were significantly increased.
两组各20名无心血管、肝脏、肾脏或胃肠道功能衰竭迹象的患者，分别口服安慰剂或每天100毫克的SB 7505，持续治疗五天。心率和血压未观察到变化。尿量、钠、钾和氯的排泄量以及肌酐清除率均显著增加。
