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克雅氏病的全脑病变型：脑白质的原发性受累。

Panencephalopathic type of Creutzfeldt-Jakob disease: primary involvement of the cerebral white matter.

作者信息

Mizutani T, Okumura A, Oda M, Shiraki H

出版信息

J Neurol Neurosurg Psychiatry. 1981 Feb;44(2):103-15. doi: 10.1136/jnnp.44.2.103.

DOI:10.1136/jnnp.44.2.103
PMID:7012278
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC490840/
Abstract

Eight necropsy cases of a "panencephalopathic" type of Creutzfeldt-Jakob disease (CJD) in the Japanese are reported. The reasons why this type should be discussed separately from other types of CJD are that there is primary involvement of the cerebral white matter as well as the cerebral cortex, and that the white matter lesion of one Japanese human brain with CJD similar to the present group has been successfully transmitted to experimental animals.

摘要

本文报告了8例日本“全脑病变型”克雅氏病（CJD）的尸检病例。之所以要将此类型与其他类型的CJD分开讨论，原因在于脑白质以及大脑皮层均有原发性病变，并且1例与本研究组类似的患CJD的日本人脑白质病变已成功传播给实验动物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/c4b58fbc2431/jnnpsyc00058-0023-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/189d9372ea32/jnnpsyc00058-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/b62a84179d62/jnnpsyc00058-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/f0af904fb606/jnnpsyc00058-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/204182044d87/jnnpsyc00058-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/46d8e46a15e4/jnnpsyc00058-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/4fb3553a2e78/jnnpsyc00058-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/c3ed9b3e2558/jnnpsyc00058-0022-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/4a526783d236/jnnpsyc00058-0022-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/c4b58fbc2431/jnnpsyc00058-0023-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/189d9372ea32/jnnpsyc00058-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/b62a84179d62/jnnpsyc00058-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/f0af904fb606/jnnpsyc00058-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/204182044d87/jnnpsyc00058-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/46d8e46a15e4/jnnpsyc00058-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/4fb3553a2e78/jnnpsyc00058-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/c3ed9b3e2558/jnnpsyc00058-0022-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/4a526783d236/jnnpsyc00058-0022-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a7/490840/c4b58fbc2431/jnnpsyc00058-0023-a.jpg

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CREUTZFELDT-JAKOB'S DISEASE. CLINICOPATHOLOGIC REPORT OF 15 CASES AND REVIEW OF THE LITERATURE (WITH SPECIAL REFERENCE TO A RELATED DISORDER DESIGNATED AS SUBACUTE SPONGIFORM ENCEPHALOPATHY).
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伴有异常长时间无动性缄默状态的 MM1 型散发性克雅氏病病例中的系统退行性变。
Prion. 2021 Dec;15(1):12-20. doi: 10.1080/19336896.2020.1868931.
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Prion and Prion-like Diseases in Humans: Poster Abstracts.人类中的朊病毒及类朊病毒疾病：海报摘要
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White matter involvement in sporadic Creutzfeldt-Jakob disease.散发性克雅氏病的白质受累。
Brain. 2014 Dec;137(Pt 12):3339-54. doi: 10.1093/brain/awu298. Epub 2014 Nov 2.
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