Abrahámová J, Májský A, Koutecký J
Onkologie. 1981 Feb;4(1):19-20. doi: 10.1159/000214870.
In 41 children with germ-cell tumors differently localised and 301 healthy unrelated subjects, 22 HLA antigens of A and B loci were tested. No statistically significant difference in the frequency of HLA antigens--with exception of a higher frequency of HLA-A28 (14,63% versus 4,32% in the controls, chi 2 = 5,69) before the correction of p value--was found. The cause of the rare associations between the tumors and HLA was discussed.
对41例不同部位生殖细胞瘤患儿及301名健康无关受试者检测了22种A和B位点的HLA抗原。除校正p值前HLA - A28频率较高(14.63%对比对照组的4.32%,χ² = 5.69)外,未发现HLA抗原频率有统计学显著差异。文中讨论了肿瘤与HLA之间罕见关联的原因。