Müller P K, Kirsch E, Gauss-Müller V, Krieg T
Mol Cell Biochem. 1981 Jan 28;34(2):73-85. doi: 10.1007/BF02354861.
We reviewed here a number of publications containing data on the quantitative aspects of collagen synthesis in vitro. In one section we discussed the factors which modulate the amount of collagen synthesized in various culture systems and in another section we presented experimental evidence for regulatory mechanisms operating in collagen synthesis on the transcriptional and/or translational levels. We believe that growing knowledge of the mechanisms controlling collagen synthesis will help us to understand and deal with fibrotic processes better.
我们在此回顾了一些包含体外胶原蛋白合成定量数据的出版物。在一个部分中，我们讨论了调节各种培养系统中胶原蛋白合成量的因素，在另一个部分中，我们提供了在转录和/或翻译水平上控制胶原蛋白合成的调节机制的实验证据。我们相信，对控制胶原蛋白合成机制的不断了解将有助于我们更好地理解和应对纤维化过程。
