Meyer R K, Burger M M, Tschannen R, Schäfer R
Arch Virol. 1981;67(1):11-8. doi: 10.1007/BF01314597.
When monolayer cultures of mouse 3T3 cells were infected with vaccinia virus, a rapid decrease of microfilament bundles was observed. The major disappearance of the cellular microfilaments occurred within the first hour after vaccinia virus infection, which is the period of uncoating of the virus core and early viral protein synthesis. The microfilament bundles of infected cells were significantly preserved in the presence of puromycin which inhibits viral protein synthesis.
当用痘苗病毒感染小鼠3T3细胞的单层培养物时,观察到微丝束迅速减少。细胞微丝的主要消失发生在痘苗病毒感染后的第一小时内,这是病毒核心脱壳和早期病毒蛋白合成的时期。在存在抑制病毒蛋白合成的嘌呤霉素的情况下,感染细胞的微丝束得到了显著保留。