Sargent T D, Yang M, Bonner J
Proc Natl Acad Sci U S A. 1981 Jan;78(1):243-6. doi: 10.1073/pnas.78.1.243.
The nucleotide sequences of the recombinant DNA inserts of three bacterial plasmid clones containing nearly all of the rat serum albumin mRNA have been determined. A statistical analysis of the nucleotide sequence reveals a pattern of repeated internal homology that confirms the "intragenic triplication" model of albumin evolution.
已测定了三个细菌质粒克隆的重组DNA插入片段的核苷酸序列,这些克隆包含了几乎所有的大鼠血清白蛋白mRNA。对核苷酸序列的统计分析揭示了一种重复的内部同源性模式,证实了白蛋白进化的“基因内三联体”模型。