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用多烯抗生素治疗后白色念珠菌菌落形成单位增加。

Increase in colony-forming units of Candida albicans after treatment with polyene antibiotics.

作者信息

Brajtburg J, Elberg S, Medoff G, Kobayashi G S

出版信息

Antimicrob Agents Chemother. 1981 Jan;19(1):199-200. doi: 10.1128/AAC.19.1.199.

DOI:10.1128/AAC.19.1.199
PMID:7018385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC181384/
Abstract

Polyene antibiotics, at concentrations which do not cause detectable toxic effect, induce an increase in the number of colon-forming units of yeast cells of Candida albicans. This effect, which we attribute to an increase in plating efficiency, is probably caused by binding of the polyenes to fatty acids in the cell wall of fungi.

摘要

多烯抗生素在不会引起可检测到的毒性作用的浓度下，会导致白色念珠菌酵母细胞的菌落形成单位数量增加。我们将这种效应归因于平板接种效率的提高，它可能是由多烯与真菌细胞壁中的脂肪酸结合所引起的。

相似文献

1
Increase in colony-forming units of Candida albicans after treatment with polyene antibiotics.用多烯抗生素治疗后白色念珠菌菌落形成单位增加。
Antimicrob Agents Chemother. 1981 Jan;19(1):199-200. doi: 10.1128/AAC.19.1.199.
2
Dissociation between ion permeability and the lethal action of polyene antibiotics on Candida albicans.离子通透性与多烯抗生素对白色念珠菌致死作用之间的解离
Antimicrob Agents Chemother. 1978 Jun;13(6):914-7. doi: 10.1128/AAC.13.6.914.
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Two types of resistance to polyene antibiotics in Candida albicans.白色念珠菌对多烯类抗生素的两种耐药类型。
Nature. 1974 Oct 18;251(5476):656-9. doi: 10.1038/251656a0.
4
The polyene macrolide antibiotics.多烯大环内酯类抗生素
Postgrad Med J. 1979 Sep;55(647):653-6. doi: 10.1136/pgmj.55.647.653.
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Effects of serum lipoproteins on damage to erythrocytes and Candida albicans cells by polyene antibiotics.血清脂蛋白对多烯抗生素所致红细胞和白色念珠菌细胞损伤的影响。
J Infect Dis. 1986 Mar;153(3):623-6. doi: 10.1093/infdis/153.3.623.
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The release of potassium ions from Candida albicans in the presence of polyene antibiotics.在多烯抗生素存在的情况下白色念珠菌中钾离子的释放。
J Gen Microbiol. 1974 Feb;80(2):451-65. doi: 10.1099/00221287-80-2-451.
7
[Properties of a Candida albicans strain possessing an increased sensitivity to polyene antibiotics].[一株对多烯抗生素敏感性增加的白色念珠菌菌株的特性]
Antibiotiki. 1978 May;23(5):411-3.
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The mode of action of polyene antibiotics; induced potassium leakage in Candida albicans.多烯抗生素的作用方式；白色念珠菌中诱导的钾离子泄漏
J Gen Microbiol. 1974 Apr;81(2):325-30. doi: 10.1099/00221287-81-2-325.
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[Action of polyene antibiotics on ribosome binding with Candida albicans membranes].
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Postantifungal effects of echinocandin, azole, and polyene antifungal agents against Candida albicans and Cryptococcus neoformans.棘白菌素类、唑类和多烯类抗真菌药物对白色念珠菌和新型隐球菌的抗真菌后效应
Antimicrob Agents Chemother. 2000 Apr;44(4):1108-11. doi: 10.1128/AAC.44.4.1108-1111.2000.

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Assessment of the effect of amphotericin B on the vitality of Candida albicans.两性霉素B对白色念珠菌活力影响的评估。
Antimicrob Agents Chemother. 1999 May;43(5):1034-41. doi: 10.1128/AAC.43.5.1034.
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Antimicrob Agents Chemother. 1984 Dec;26(6):892-7. doi: 10.1128/AAC.26.6.892.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Factors affecting the absorption of nystatin by Candida albicans.
Ann Biochem Exp Med. 1963 Mar;23:101-12.
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Application of differential spectra in the ultraviolet-visible region to study the formation of amphotericin B-sterol complexes.
Biochim Biophys Acta. 1980 Nov 4;602(2):260-8. doi: 10.1016/0005-2736(80)90309-0.
4
Effect of fatty acids on action of polyene antibiotics.脂肪酸对多烯抗生素作用的影响。
Antimicrob Agents Chemother. 1980 May;17(5):861-4. doi: 10.1128/AAC.17.5.861.
5
Characterization of the binding of amphotericin B to Saccharomyces cerevisiae and relationship to the antifungal effects.两性霉素B与酿酒酵母结合的特性及其与抗真菌作用的关系。
Antimicrob Agents Chemother. 1974 Dec;6(6):770-6. doi: 10.1128/AAC.6.6.770.
6
Fungal sterols and the mode of action of the polyene antibiotics.真菌甾醇与多烯抗生素的作用方式
Adv Appl Microbiol. 1974;17(0):109-34. doi: 10.1016/s0065-2164(08)70556-2.
7
The release of potassium ions from Candida albicans in the presence of polyene antibiotics.在多烯抗生素存在的情况下白色念珠菌中钾离子的释放。
J Gen Microbiol. 1974 Feb;80(2):451-65. doi: 10.1099/00221287-80-2-451.
8
Mode of action of the polyene antibiotic candicidin: binding factors in the wall of Candida albicans.多烯抗生素杀假丝菌素的作用模式：白色念珠菌细胞壁中的结合因子
Antimicrob Agents Chemother. 1976 Apr;9(4):561-8. doi: 10.1128/AAC.9.4.561.
9
Polyene antibiotic - sterol interaction.多烯抗生素 - 固醇相互作用
Adv Lipid Res. 1976;14:127-70.
10
Relationship between the antibiotic and immunoadjuvant effects of amphotericin B methyl ester.
Immunochemistry. 1978 Apr;15(4):219-24. doi: 10.1016/0161-5890(78)90058-5.