Brajtburg J, Elberg S, Medoff G, Kobayashi G S
Antimicrob Agents Chemother. 1981 Jan;19(1):199-200. doi: 10.1128/AAC.19.1.199.
Polyene antibiotics, at concentrations which do not cause detectable toxic effect, induce an increase in the number of colon-forming units of yeast cells of Candida albicans. This effect, which we attribute to an increase in plating efficiency, is probably caused by binding of the polyenes to fatty acids in the cell wall of fungi.
多烯抗生素在不会引起可检测到的毒性作用的浓度下,会导致白色念珠菌酵母细胞的菌落形成单位数量增加。我们将这种效应归因于平板接种效率的提高,它可能是由多烯与真菌细胞壁中的脂肪酸结合所引起的。