Singer R A, Johnston G C
Proc Natl Acad Sci U S A. 1981 May;78(5):3030-3. doi: 10.1073/pnas.78.5.3030.
Under conditions that protract the S phase for Saccharomyces cerevisiae without affecting steady-state rates of cell growth or proliferation, there were striking decreases in the length of the G1 period. These decreases were localized in the period between mitosis and the start event that initiates a new cell cycle. We conclude that this major fraction of the G1 period has no functional role in the DNA-division sequence of cell cycle events.
在延长酿酒酵母S期而不影响细胞生长或增殖稳态速率的条件下,G1期长度显著缩短。这些缩短发生在有丝分裂和启动新细胞周期的起始事件之间的时间段内。我们得出结论,G1期的这一主要部分在细胞周期事件的DNA分裂序列中没有功能作用。