Simmen H P, Rieder H, Bonetti A, Lüthy R
Dtsch Med Wochenschr. 1981 Jul 17;106(29-30):946-50. doi: 10.1055/s-2008-1070432.
Four methods were used to assess gentamicin concentrations in 37 sera of patients treated with gentamicin. It was shown that the bioassay (agar diffusion) and the enzyme immunoassay correlated well, and the latex agglutination inhibition test badly, with the radioenzyme assay which was used as the reference method. Among presently available methods only the bioassay can be performed with relatively little equipment.
采用四种方法对37例接受庆大霉素治疗患者的血清中的庆大霉素浓度进行评估。结果显示,生物测定法(琼脂扩散法)和酶免疫测定法与用作参考方法的放射酶测定法相关性良好,而乳胶凝集抑制试验与放射酶测定法相关性较差。在目前可用的方法中,只有生物测定法所需设备相对较少。