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给予卡托普利的小鼠近球细胞粗面内质网中致密颗粒的出现。

Appearance of dense granules in the rough endoplasmic reticulum of the juxtaglomerular cells in mice administered with captopril.

作者信息

Kaneta M, Abe K, Ito T

出版信息

Cell Tissue Res. 1981;220(1):219-22. doi: 10.1007/BF00209980.

DOI:10.1007/BF00209980
PMID:7023690
Abstract

Captopril [1-(D-3-mercapto-2-methyl-1-oxopropyl)-L-proline (S,S)] is now known to be an inhibitor of angiotensin-converting enzyme. In male mice, the juxtaglomerular cells were examined by electron microscopy 42 h after administration of captopril. Numerous dense granules appeared in the rough endoplasmic reticulum of these cells.

摘要

卡托普利[1-(D-3-巯基-2-甲基-1-氧代丙基)-L-脯氨酸(S,S)]现已被确认为一种血管紧张素转换酶抑制剂。在雄性小鼠中，给药卡托普利42小时后，通过电子显微镜检查肾小球旁细胞。这些细胞的粗面内质网中出现了大量致密颗粒。

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本文引用的文献

1
PROTEIN SYNTHESIS, STORAGE, AND DISCHARGE IN THE PANCREATIC EXOCRINE CELL. AN AUTORADIOGRAPHIC STUDY.胰腺外分泌细胞中的蛋白质合成、储存与释放。一项放射自显影研究。
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Intracisternal granules in the exocrine cells of the pancreas.胰腺外分泌细胞中的脑池内颗粒。
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Renin in the submaxillary gland: a review.颌下腺中的肾素：综述
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Genesis of juxtaglomerular cell granules. A physiologic, light and electron microscopic study concerning experimental renal hypertension.肾小球旁细胞颗粒的起源。一项关于实验性肾性高血压的生理学、光学和电子显微镜研究。
Lab Invest. 1965 Oct;14(10):1834-47.
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Fine structure of the venom gland epithelium of the South American rattlesnake and radioautographic studies of protein formation by the secretory cells.南美响尾蛇毒腺上皮的精细结构以及分泌细胞蛋白质形成的放射自显影研究。
Am J Anat. 1973 Sep;138(1):79-119. doi: 10.1002/aja.1001380106.
6
Studies on the juxtaglomerular apparatus. II. Quantitative morphology after adrenalectomy.肾小球旁器的研究。II. 肾上腺切除术后的定量形态学
Cell Tissue Res. 1974;151(4):457-69. doi: 10.1007/BF00222991.
7
The ultrastructural pathology of the rat epididymis after administration of -chlorhydrin (U-5897). I. Effects of a single high dose.给予氯乙醇（U - 5897）后大鼠附睾的超微结构病理学。I. 单次高剂量的影响。
Anat Rec. 1973 Feb;175(2):203-29. doi: 10.1002/ar.1091750206.
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Purification of high molecular weight forms of renin from hog kidney.从猪肾中纯化高分子量形式的肾素。
Circ Res. 1977 Oct;41(4 Suppl 2):11-6. doi: 10.1161/01.res.41.4.11.
9
Renin synthesis, storage, and release in the rat: a morphological and biochemical study.大鼠中肾素的合成、储存及释放：一项形态学与生物化学研究。
Kidney Int. 1977 Mar;11(3):161-9. doi: 10.1038/ki.1977.24.
10
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Kaibogaku Zasshi. 1979 Oct;54(5):251-9.