Murphy G F, Bhan A K, Sato S, Harrist T J, Mihm M C
Lab Invest. 1981 Nov;45(5):465-8.
Intraepidermal dendritic cells react with the monoclonal antibody, anti-T6, which also reacts with a majority of cortical thymocytes but not with mature T lymphocytes. Application of a four-step peroxidase antiperoxidase technique and immunoelectron microscopy to normal human epidermis demonstrates that T6 antigen is present on the cell surface of Langerhans cells but not on keratinocytes or melanocytes. These data suggest that T6 antigen is an important marker for Langerhans cells.
表皮内树突状细胞与单克隆抗体抗-T6发生反应，抗-T6也与大多数皮质胸腺细胞发生反应，但不与成熟T淋巴细胞发生反应。将四步法过氧化物酶抗过氧化物酶技术和免疫电子显微镜应用于正常人表皮，结果表明T6抗原存在于朗格汉斯细胞的细胞表面，而不存在于角质形成细胞或黑素细胞表面。这些数据表明T6抗原是朗格汉斯细胞的重要标志物。
