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A clinical comparison of tobramycin and gentamicin sulfate in the treatment of ocular infections.

作者信息

Laibson P, Michaud R, Smolin G, Okumoto M, Rosenthal A, Cagle G

出版信息

Am J Ophthalmol. 1981 Dec;92(6):836-41. doi: 10.1016/s0002-9394(14)75639-9.

DOI:10.1016/s0002-9394(14)75639-9
PMID:7032304
Abstract

We evaluated the safety and efficacy of tobramycin and gentamicin sulfate ophthalmic solutions in the treatment of patients with bacterial infections of the conjunctivas. In this double-masked study involving 66 patients, the two aminoglycosides were found to be equally safe and effective, although the in vitro data suggested that tobramycin may be more efficacious against Pseudomonas infections. Staphylococcus aureus and S. epidermidis were the most frequent isolates from the infected eyes (59.8% and 20.6%, respectively).

摘要

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