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布地奈德——一种新型鼻用类固醇。布地奈德与安慰剂治疗季节性变应性鼻炎患者的双盲临床对照研究。

Budesonide - a new steroid for intranasal use. A double-blind clinical comparison between budesonide and placebo in patients with seasonal allergic rhinitis.

作者信息

Warland A, Møller P, Lindqvist N

出版信息

Allergy. 1981 Aug;36(6):425-8. doi: 10.1111/j.1398-9995.1981.tb01849.x.

DOI:10.1111/j.1398-9995.1981.tb01849.x
PMID:7032343
Abstract

Twenty-nine patients with seasonal rhinitis completed a double-blind study comparing budesonide nasal spray 200 micrograms b.i.d. with placebo. The patients were randomly assigned into two parallel groups. Symptoms were assessed over a treatment period of 3 weeks. There were statistically significant differences in favour of budesonide on all measurements. Side effects were mild and the incidence was low.

摘要

29名季节性鼻炎患者完成了一项双盲研究,比较每日两次使用200微克布地奈德鼻喷雾剂与使用安慰剂的效果。患者被随机分为两个平行组。在3周的治疗期内对症状进行评估。在所有测量指标上,布地奈德组均有统计学上的显著优势。副作用轻微,发生率较低。

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