厌氧菌介导的2-硝基芴和2-氨基芴对鼠伤寒沙门氏菌的致突变性。
The anaerobe-mediated mutagenicity of 2-nitrofluorene and 2-aminofluorene for Salmonella typhimurium.
作者信息
Karpinsky G E, Rosenkranz H S
出版信息
Environ Mutagen. 1980;2(3):353-8. doi: 10.1002/em.2860020305.
PMID:7032900
Abstract
Anaerobic bacteria (Bacteroides fragilis, B vulgatus, and B thetaiotaomicron) possess the enzymic ability to convert 2-nitrofluorene and 2-aminofluorene to substances mutagenic for Salmonella typhimurium. If it be assumed that the active intermediate for both chemicals is 2-hydroxylaminofluorene, then these bacteria possess reductive as well as oxidative capabilities.
摘要
厌氧细菌（脆弱拟杆菌、普通拟杆菌和嗜内脏拟杆菌）具有将2-硝基芴和2-氨基芴转化为对鼠伤寒沙门氏菌有诱变作用的物质的酶促能力。如果假定这两种化学物质的活性中间体都是2-羟基氨基芴，那么这些细菌同时具备还原能力和氧化能力。
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