Dattani I M, Gerken A, Evans B A
Br J Vener Dis. 1982 Feb;58(1):32-5. doi: 10.1136/sti.58.1.32.
In a study of 100 women with non-specific vaginitis, characterised by a vaginal discharge which was malodorous and pruritic in most cases and caused dyspareunia and dysuria in some, Gardnerella vaginalis was isolated in 46% of patients. When present, G vaginalis was significantly associated with Mycoplasma hominis and Bacteroides species. Isolation of G vaginalis was unrelated to the presenting symptoms. Treatment with povidone-iodine pessaries for two weeks produced no pronounced benefit, either clinically or microbiologically, compared with a placebo. Nevertheless, 68% of all patients followed reported improvement four weeks after the start of treatment. The findings suggest that G vaginalis is one cause of non-specific vaginitis, which is more likely to be seen in women using oral contraceptives and is usually cured spontaneously.
在一项针对100名患有非特异性阴道炎的女性的研究中，其特征为多数病例出现有异味且瘙痒的阴道分泌物，部分病例伴有性交困难和排尿困难，46%的患者分离出阴道加德纳菌。阴道加德纳菌出现时，与解脲脲原体和拟杆菌属显著相关。阴道加德纳菌的分离与所呈现的症状无关。与安慰剂相比，使用聚维酮碘阴道栓剂治疗两周在临床或微生物学方面均未产生明显益处。然而，所有接受随访的患者中有68%报告在治疗开始四周后症状有所改善。研究结果表明，阴道加德纳菌是非特异性阴道炎的一个病因，在使用口服避孕药的女性中更易出现且通常可自愈。
