Nissen-Meyer R, Kjellgren K, Mansson B
Recent Results Cancer Res. 1982;80:142-8. doi: 10.1007/978-3-642-81685-7_24.
One single course of i.v. cyclophosphamide (30 mg/kg) was given over a 6-day period to 559 mastectomized patients. During a follow-up period of up to 15 years, 241 recurrence and 234 deaths are registered in this group, and 294 recurrences and 283 deaths in the randomized control group of 577 patients. Analysis of the life-table curves shows an increased cure rate of about 10%.
对559例接受乳房切除术的患者在6天内静脉注射单疗程环磷酰胺（30mg/kg）。在长达15年的随访期内，该组登记有241例复发和234例死亡，在577例患者的随机对照组中有294例复发和283例死亡。生命表曲线分析显示治愈率提高了约10%。
