Mayor G H, Sprague S M, Sanchez T V
Am J Kidney Dis. 1981 Nov;1(3):141-5. doi: 10.1016/s0272-6386(81)80019-4.
These data taken together might indicate that increased tissue burdens of aluminum begin early in chronic renal disease as a consequence of oral aluminum administration. The initiation of dialysis leads to additional aluminum exposure via dialysate. Elevated endogenous parathyroid hormone levels could further enhance the absorption of orally ingested aluminum and alter tissue distribution of aluminum resulting in high brain aluminum concentration.
综合这些数据可能表明，由于口服铝剂，慢性肾病早期组织中的铝负荷就开始增加。开始透析会通过透析液导致额外的铝暴露。内源性甲状旁腺激素水平升高会进一步增强口服摄入铝的吸收，并改变铝的组织分布，导致脑铝浓度升高。
