小肠腺癌并发克罗恩病

Hawker P C, Gyde S N, Thompson H, Allan R N

Gut. 1982 Mar;23(3):188-93. doi: 10.1136/gut.23.3.188.

Adenocarcinoma of the small intestine is an uncommon complication of Crohn's disease. We report the clinical and pathological details of three cases diagnosed between 1968 and 1980 with a review of 58 cases from the literature. Of the 61 cases, 41 tumours occurred in the ileum, 18 in the jejunum, one in the duodenum and ileum, and one in the ileum and colon. Eighteen occurred in bypassed intestinal loops. The prognosis was poor: 44 patients (72%) had died with a mean interval of only 7.9 months from the diagnosis of cancer.

小肠腺癌是克罗恩病的一种罕见并发症。我们报告了1968年至1980年间确诊的3例病例的临床和病理细节，并对文献中的58例病例进行了回顾。在这61例病例中，41例肿瘤发生在回肠，18例在空肠，1例在十二指肠和回肠，1例在回肠和结肠。18例发生在旷置的肠袢。预后较差：44例患者（72%）已死亡，从癌症诊断起平均间隔仅7.9个月。