一名患有未确诊的回肠末端克罗恩病的患者出现了两个同步性小肠腺癌。

Two synchronous adenocarcinomas of the small bowel in a patient with undiagnosed Crohn's disease of the terminal ileum.

作者信息

Sammartino P, Sibio S, Di Giorgio A, Caronna R, Viscido A, Zippi M, Biacchi D, Accarpio F, Mingazzini P, Caprilli R

机构信息

Dipartimento di Chirurgia P. Valdoni, University of Rome La Sapienza, Policlinico Umberto I, Via Lancisi, 2-00185, Rome, Italy.

出版信息

Int J Colorectal Dis. 2006 May;21(4):388-91. doi: 10.1007/s00384-005-0005-5. Epub 2005 Jul 30.

DOI:10.1007/s00384-005-0005-5

PMID:16059693

Abstract

A small but significant excess of deaths for tumors of the digestive system has been described in Crohn's disease. In a study analyzing all cancers of the small intestine within a defined population, Crohn's disease was the major underlying factor for cancer of the small intestine. Areas of the small intestine containing strictures are unusually prone to malignant transformation. We report the rare case of a patient in whom surgery for intestinal occlusion disclosed Crohn's disease of the distal ileum complicated by two adenocarcinomas arising within distinct areas of the inflamed bowel.

摘要

克罗恩病患者消化系统肿瘤的死亡人数虽少但有显著增加。在一项分析特定人群中所有小肠癌的研究中，克罗恩病是小肠癌的主要潜在因素。小肠出现狭窄的部位异常容易发生恶性转化。我们报告了一例罕见病例，该患者因肠梗阻接受手术，术中发现回肠末端克罗恩病，并伴有在炎症肠段不同区域发生的两例腺癌。