Myers M G, Rasley D A, Hierholzer W J
Pediatrics. 1982 Aug;70(2):199-202.
More than 500 hospital employees and 209 patients were exposed to varicella zoster virus (VZV) as a consequence of 22 uncontrolled hospital introductions that occurred over a period of 34 months. Five introductions of varicella were by hospital employees who acquired the infection outside the hospital. Successful infection control of VZV requires an accurate definition of the susceptible population and the limitation of transmission. Individuals with prior VZV infection are epidemiologically not at risk for developing clinical illness. Serologic screening of hospital employees with uncertain prior VZV history is effective in identifying those at risk of developing the infection. A prior history of intimate exposure to VZV does not imply immunity in the absence of clinical illness.
在34个月的时间里，由于22起未得到控制的医院内水痘-带状疱疹病毒（VZV）传入事件，超过500名医院员工和209名患者接触到了该病毒。5起水痘传入事件是由在医院外感染的医院员工引起的。成功控制VZV感染需要准确界定易感人群并限制传播。既往感染过VZV的个体在流行病学上没有发生临床疾病的风险。对既往VZV感染史不明确的医院员工进行血清学筛查，对于识别有感染风险的人员是有效的。在没有临床疾病的情况下，既往有密切接触VZV的病史并不意味着具有免疫力。
