Fukui T, Kakiuchi N, Ikehara M
Biochim Biophys Acta. 1982 May 31;697(2):174-7. doi: 10.1016/0167-4781(82)90074-4.
Poly(2'-fluoro-2'-deoxyadenylic acid), poly(2'-chloro-2'-deoxyadenylic acid) and poly(2'-bromo-2'-deoxyadenylic acid) are used as messenger RNAs in protein synthesizing systems in vitro. All polynucleotides were active as messengers and [14 C]lysine was incorporated into polypeptides. The initial velocity of polylysine formation was greater using poly(2'-fluoro-2'-deoxyadenylic acid) as messenger than in the case of poly(rA), and all synthetic messengers lived longer in the protein synthetic system.
聚（2'-氟-2'-脱氧腺苷酸）、聚（2'-氯-2'-脱氧腺苷酸）和聚（2'-溴-2'-脱氧腺苷酸）在体外蛋白质合成系统中用作信使核糖核酸。所有多核苷酸作为信使都具有活性，并且[14C]赖氨酸被掺入多肽中。以聚（2'-氟-2'-脱氧腺苷酸）作为信使时聚赖氨酸形成的初始速度比以聚（rA）为信使时更快，并且所有合成信使在蛋白质合成系统中的寿命更长。
