Salminen S, Salminen E, Marks V
Diabetologia. 1982 Jun;22(6):480-2. doi: 10.1007/BF00282594.
Xylitol given by gavage to unadapted rats produced profound diarrhoea and no rise in plasma gastric inhibitory polypeptide (GIP) concentration. In xylitol adapted rats it did not cause diarrhoea but still had no effect upon GIP release in contrast to glucose, which did. In healthy human subjects xylitol taken by mouth in solution as a single 30 g dose produced only a minimal rise in blood glucose and no rise in plasma GIP or insulin concentration. Glucose in similar doses, on the other hand, caused a large rise in all three.
给未适应的大鼠灌胃木糖醇会导致严重腹泻，且血浆胃抑制性多肽（GIP）浓度无升高。在适应了木糖醇的大鼠中，它不会引起腹泻，但与葡萄糖不同，对GIP释放仍无影响，而葡萄糖会影响GIP释放。在健康人类受试者中，单次口服30克溶液形式的木糖醇只会使血糖略有升高，血浆GIP或胰岛素浓度无升高。另一方面，相同剂量的葡萄糖会使这三者都大幅升高。
