Gragnoli G, Tanganelli I, Signorini A M, Tarli P, Paoli C
Acta Diabetol Lat. 1982 Apr-Jun;19(2):161-6. doi: 10.1007/BF02581152.
In 44 diabetic patients treated either with insulin or with oral antidiabetic agents, non-enzymatic glycosylation of serum proteins (GSP), expressed as nmol of 5-hydroxymethylfurfural/mg protein, showed higher values than those found in control subjects. In the diabetic GSP was more closely correlated to the degree of glycometabolic control during the 15 days preceding the assay, than to the glycosylated hemoglobin (HbA1). However, GSP values did not correlate significantly with fasting blood glucose levels. It may be concluded that GSP can be used as an index of the medium-term control of diabetes mellitus.
在44例接受胰岛素或口服抗糖尿病药物治疗的糖尿病患者中，血清蛋白非酶糖基化（GSP），以5-羟甲基糠醛的纳摩尔数/毫克蛋白表示，其值高于对照组。在糖尿病患者中，GSP与检测前15天的糖代谢控制程度的相关性，比与糖化血红蛋白（HbA1）的相关性更强。然而，GSP值与空腹血糖水平无显著相关性。可以得出结论，GSP可作为糖尿病中期控制的一个指标。
