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白塞病中的多形核细胞功能

Polymorphonuclear function in Behçet's syndrome.

作者信息

Fordham J N, Davies P G, Kirk A, Currey H L

出版信息

Ann Rheum Dis. 1982 Aug;41(4):421-5. doi: 10.1136/ard.41.4.421.

Abstract

Three aspects of polymorphonuclear leucocyte (PMN) function were studied in 19 patients with Behçet's syndrome (BS). By 2 different techniques directed motility was found to be increased. This increase was largely due to the subgroup of patients with ocular involvement. Counts of absolute numbers of cells migrating highlighted this finding. No difference was found in the phagocytic or adherent properties of PMN in Behçet's syndrome. Increased PMN motility in Behçet's syndrome may contribute to the expression of the syndrome. It remains to be tested whether altered PMN motility in this syndrome is genetically linked.

摘要

对19例白塞病(BS)患者的多形核白细胞(PMN)功能的三个方面进行了研究。通过2种不同技术发现趋化运动增加。这种增加主要归因于有眼部受累的患者亚组。对迁移细胞的绝对数量计数突出了这一发现。白塞病患者的PMN吞噬或黏附特性未发现差异。白塞病中PMN运动性增加可能促成了该综合征的表现。该综合征中PMN运动性改变是否与基因相关仍有待检验。

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