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一名口腔外科医生传播乙型肝炎。

Transmission of hepatitis B by an oral surgeon.

作者信息

Reingold A L, Kane M A, Murphy B L, Checko P, Francis D P, Maynard J E

出版信息

J Infect Dis. 1982 Feb;145(2):262-8. doi: 10.1093/infdis/145.2.262.

Abstract

An outbreak of hepatitis B in southeastern Connecticut was traced to an oral surgeon. In a serosurvey of his 754 noninstitutionalized patients, 511 (68%) participated. The rates of seropositivity for hepatitis B surface antigen (HBsAg) or antibody to HBsAg by year of oral surgery were 4.8% in 1977, 7.4% in 1978, and 14.8% in 1979. The transmission of hepatitis B, as measured by seropositivity, occurred between November 1978 and August 1979; the peak transmission was in February (31.2% seropositivity). Seropositivity was strongly correlated with the extent of surgical trauma (P less than 0.0001). HBsAg subtyping revealed that the oral surgeon and all four subtypable patients demonstrated both d and y reactivity, as did the patient from whom it was most likely the oral surgeon acquired his infection: a mentally retarded patient who had 24 extraction in March 1978. This study demonstrates that the transmission of hepatitis B between dental practitioners and their patients frequently results in subclinical infections.

摘要

康涅狄格州东南部的一次乙型肝炎暴发被追溯到一位口腔外科医生。在对他的754名非住院患者进行的血清学调查中,511人(68%)参与了调查。按口腔手术年份划分的乙型肝炎表面抗原(HBsAg)或抗HBsAg抗体的血清阳性率在1977年为4.8%,1978年为7.4%,1979年为14.8%。以血清阳性率衡量的乙型肝炎传播发生在1978年11月至1979年8月之间;传播高峰在2月(血清阳性率为31.2%)。血清阳性与手术创伤程度密切相关(P<0.0001)。HBsAg亚型分析显示,这位口腔外科医生以及所有四名可进行亚型分析的患者均表现出d和y反应性,很可能是这位口腔外科医生感染源的那名患者也是如此:一名智障患者,于1978年3月接受了24次拔牙手术。这项研究表明,牙科医生与其患者之间的乙型肝炎传播常常导致亚临床感染。

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