Cozanitis D A, Krieg N P, Agelink H, Crul J F
South Med J. 1982 Feb;75(2):179-81. doi: 10.1097/00007611-198202000-00015.
The possibility of using the longer acting antimuscarinic drug glycopyrrolate intramuscularly to prevent the bradycardia that sometimes results from successive doses of succinylcholine was examined. Atropine, in an equipotent dose, was given to another group of patients for comparison. Glycopyrrolate was as ineffective as atropine in preventing bradycardia. Later, a third group of patients who received no antimuscarinic drug was studied as controls. This last group had no more bradycardia than the other two groups.
研究了肌内注射长效抗毒蕈碱药物格隆溴铵以预防有时因连续给予琥珀酰胆碱而导致的心动过缓的可能性。给另一组患者给予等效剂量的阿托品作为对照。格隆溴铵在预防心动过缓方面与阿托品一样无效。后来，将第三组未接受抗毒蕈碱药物的患者作为对照进行研究。最后一组的心动过缓情况并不比其他两组多。
