Cozanitis D A, Dundee J W, Khan M M
Br J Anaesth. 1980 Mar;52(3):291-3. doi: 10.1093/bja/52.3.291.
The effectiveness of atropine and glycopyrrolate in the prophylaxis of suxamethonium-induced bradycardia was evaluated in a double-blind study of 56 patients. Three had clinically demonstrable bradycardia, all having received atropine. We conclude that glycopyrrolate offered adequate protection against cardiac effects of repeated doses of suxamethonium.
在一项针对56名患者的双盲研究中,评估了阿托品和格隆溴铵预防琥珀酰胆碱诱发心动过缓的有效性。有3例出现临床可证实的心动过缓,所有患者均接受了阿托品治疗。我们得出结论,格隆溴铵能为重复给予琥珀酰胆碱所致的心脏效应提供充分保护。