Karlmark B, Jaeger P, Fein H, Giebisch G
Am J Physiol. 1982 Jan;242(1):F95-9. doi: 10.1152/ajprenal.1982.242.1.F95.
A modification of the coulometric acid-base titration method is described for the measurement of titratable acid and ammonium in nanoliter samples. The main components consist of a pH-seeking device and a miniaturized antimony electrode system capable of delivering OH- ions at a known rate. The modifications include use of a cup-shaped pH-sensitive glass-membrane electrode for monitoring pH changes during titration and a new electronic titration circuit consisting of a high-impedance differential electrometer, a constant-current source, and an electronic integrating circuit. Details regarding the construction of the components of the titration system and practical aspects of its use are also provided.
本文描述了一种库仑酸碱滴定法的改进方法，用于测量纳升样品中的可滴定酸和铵。主要组件包括一个寻pH装置和一个能够以已知速率输送OH-离子的小型化锑电极系统。改进之处包括使用杯形pH敏感玻璃膜电极监测滴定过程中的pH变化，以及一个由高阻抗差分静电计、恒流源和电子积分电路组成的新型电子滴定电路。还提供了滴定系统组件构造的详细信息及其使用的实际方面。
