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抗生素和化疗药物对耻垢分枝杆菌中14C前体掺入的抑制作用。

Inhibition of the incorporation of 14C-precursors in Mycobacterium smegmatis by antibiotics and chemotherapeutics.

作者信息

Majtán V

出版信息

Folia Microbiol (Praha). 1982;27(1):43-8. doi: 10.1007/BF02883837.

DOI:10.1007/BF02883837
PMID:7061029
Abstract

Twenty antituberculostatics and twelve other compounds were divided into three groups according to their ability to influence the rate of incorporation of 14C-adenine and 14C-leucine in M. smegmatis. The first group includes compounds significantly inhibiting the incorporation of 14C-leucine, the second group comprises compounds inhibiting simultaneously the incorporation of both 14C-precursors, the third group contains compounds that do not bring about a 50% decrease of the rate of incorporation even at a concentration of 400 micrograms/mL.

摘要

根据20种抗结核药和12种其他化合物对耻垢分枝杆菌中14C-腺嘌呤和14C-亮氨酸掺入率的影响能力,将它们分为三组。第一组包括能显著抑制14C-亮氨酸掺入的化合物,第二组包含同时抑制两种14C前体掺入的化合物,第三组含有即使在浓度为400微克/毫升时也不会使掺入率降低50%的化合物。

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本文引用的文献

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Studies on Carbon Metabolism of Organisms of the Genus Mycobacterium: II. Utilization of Organic Compounds in a Synthetic Medium.分枝杆菌属生物的碳代谢研究:II. 合成培养基中有机化合物的利用
J Bacteriol. 1931 May;21(5):361-74. doi: 10.1128/jb.21.5.361-374.1931.
2
STREPTOMYCINOID ANTIBIOTICS: SYNERGISM BY PUROMYCIN.链霉菌素类抗生素:嘌呤霉素的协同作用
Science. 1964 Nov 6;146(3645):772-4. doi: 10.1126/science.146.3645.772.
3
Effect of 2,3-dinitrilo-1,4-dithia-9,10-anthraquinone on Mycobacterium smegmatis.2,3-二腈基-1,4-二硫杂-9,10-蒽醌对耻垢分枝杆菌的作用
Folia Microbiol (Praha). 1980;25(5):403-11. doi: 10.1007/BF02876693.
4
Dynamics of growth of atypical mycobacteria in different liquid cultivation media.非结核分枝杆菌在不同液体培养基中的生长动力学
Folia Microbiol (Praha). 1980;25(4):347-53. doi: 10.1007/BF02876618.
5
Effects of antibiotics on the uptake of 35S-methionine and 32PO4 and on their incorporation into protein and ribonucleic acid of green tobacco leaves.抗生素对绿色烟草叶片吸收35S-甲硫氨酸和32PO4及其掺入蛋白质和核糖核酸的影响。
Nature. 1965 May 22;206(4986):783-4. doi: 10.1038/206783a0.
6
Effects of ethionamide and isoxyl on mycolic acid synthesis in Mycobacterium tuberculosis BCG.
J Gen Microbiol. 1971 Jun;66(3):379-80. doi: 10.1099/00221287-66-3-379.
7
Susceptibility of mycobacterial D-alanyl-D-alanine synthetase to D-cycloserine.
Am Rev Respir Dis. 1969 Oct;100(4):579-81. doi: 10.1164/arrd.1969.100.4.579.
8
Mechanism of action of rifampin on Mycobacterium smegmatis.利福平对耻垢分枝杆菌的作用机制。
J Bacteriol. 1971 Nov;108(2):737-41. doi: 10.1128/jb.108.2.737-741.1971.
9
The effect of thiol-combining agents on polypeptide synthesis in cell-free system from Escherichia coli.硫醇结合剂对大肠杆菌无细胞系统中多肽合成的影响。
Biochem Pharmacol. 1974 Oct 1;23(19):2751-9. doi: 10.1016/0006-2952(74)90045-8.
10
Mode of action of kanamycin on Mycobacterium bovis BCG.
Am Rev Respir Dis. 1973 Jul;108(1):101-7. doi: 10.1164/arrd.1973.108.1.101.