Tozman E C, Urowitz M B, Gladman D D
Ann Rheum Dis. 1982 Feb;41(1):39-40. doi: 10.1136/ard.41.1.39.
Of 160 patients with systemic lupus erythematosus followed up in a long-term prospective study 4 with previously severe disease are in complete remission and have required no therapy for a median time of 75 months. The 4 females all presented with systemic features and a typical butterfly rash prompting early diagnosis and treatment. All patients have had complete remission of clinical and laboratory features of disease, without maintenance suppressive therapy.
在一项长期前瞻性研究中对160例系统性红斑狼疮患者进行随访，其中4例曾患有严重疾病，目前处于完全缓解状态，中位时间75个月未接受治疗。这4名女性均表现出全身症状和典型的蝶形红斑，促使早期诊断和治疗。所有患者的疾病临床和实验室特征均完全缓解，无需维持性抑制治疗。
