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既往重度系统性红斑狼疮患者出现长期完全缓解。

Prolonged complete remission in previously severe SLE.

作者信息

Tozman E C, Urowitz M B, Gladman D D

出版信息

Ann Rheum Dis. 1982 Feb;41(1):39-40. doi: 10.1136/ard.41.1.39.

Abstract

Of 160 patients with systemic lupus erythematosus followed up in a long-term prospective study 4 with previously severe disease are in complete remission and have required no therapy for a median time of 75 months. The 4 females all presented with systemic features and a typical butterfly rash prompting early diagnosis and treatment. All patients have had complete remission of clinical and laboratory features of disease, without maintenance suppressive therapy.

摘要

在一项长期前瞻性研究中对160例系统性红斑狼疮患者进行随访,其中4例曾患有严重疾病,目前处于完全缓解状态,中位时间75个月未接受治疗。这4名女性均表现出全身症状和典型的蝶形红斑,促使早期诊断和治疗。所有患者的疾病临床和实验室特征均完全缓解,无需维持性抑制治疗。

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本文引用的文献

1
OBSERVATIONS ON THE NATURAL COURSE OF DISSEMINATED LUPUS ERYTHEMATOSUS.播散性红斑狼疮自然病程的观察
Medicine (Baltimore). 1964 May;43:387-91. doi: 10.1097/00005792-196405000-00016.
4
Late mortality in SLE--"the price we pay for control".
J Rheumatol. 1980 May-Jun;7(3):412-6.
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Late-stage lupus nephropathy.
J Rheumatol. 1974 Jun;1(2):166-75.
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Steroid-induced morbidity mimicking active systemic lupus erythematosus.
Ann Intern Med. 1973 Apr;78(4):558-60. doi: 10.7326/0003-4819-78-4-558.

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