O'Connor M J, Schwartz M L, McQuarrie D G, Sumer H W
Arch Surg. 1982 Apr;117(4):437-41. doi: 10.1001/archsurg.1982.01380280031007.
A retrospective study of 65 patients with biliary sepsis and mechanical biliary obstruction, 19 of them with suppurative cholangitis (SC) and 46 with nonsuppurative cholangitis (NSC), was undertaken to identify distinguishing characteristics of the two forms of the disease. There were no statistically significant differences between SC and NSC based on histologic data, physical findings, or preoperative laboratory values. Mortality was significantly increased in patients with SC and in those with both forms of the disease who were given medical therapy alone. The treatment of choice for cholangitis with mechanical biliary obstruction is early operative drainage of the biliary tree, regardless of the presence or absence of suppuration in the common bile duct.
对65例胆源性败血症和机械性胆管梗阻患者进行了一项回顾性研究，其中19例为化脓性胆管炎（SC），46例为非化脓性胆管炎（NSC），旨在确定这两种疾病形式的区别特征。基于组织学数据、体格检查结果或术前实验室值，SC和NSC之间没有统计学上的显著差异。SC患者以及仅接受药物治疗的两种疾病形式患者的死亡率显著增加。对于机械性胆管梗阻性胆管炎，无论胆总管是否存在化脓，首选的治疗方法是早期对胆管树进行手术引流。
