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1951 - 1981年接受治疗的高血压患者的预后

Prognosis of treated hypertension 1951-1981.

作者信息

Bulpitt C J

出版信息

Br J Clin Pharmacol. 1982 Jan;13(1):73-9. doi: 10.1111/j.1365-2125.1982.tb01340.x.

Abstract

1 The 5 year survival of hypertensive patients in several studies was reviewed to demonstrate the adverse effects of increasing age, being male, having a higher untreated blood pressure of severe retinal changes. 2 The decrease in survival with increase in diastolic blood pressure was not linear, mortality being relatively constant below 90 mmHg. 3 The adverse effect of severe retinal changes was independent of the untreated blood pressure. 4 In patients selected with mild hypertension, 5 year survival can exceed 97% even when untreated. 5 Owing to the lack of suitable data we cannot conclude that treatment was more effective in prolonging life in the 1970s than in previous decades. 6 In the United States non-white patients with hypertension fared worse than white patients. 7 The serum cholesterol was not positively related to mortality in treated hypertension patients. 8 Treated hypertensive patients who smoked had at least a two-fold increase in mortality over those who did not. 9 Treated patients under the age of 50 years had a four-fold increase in mortality compared with the general population. This was greater than any excess mortality observed in the elderly.

摘要
  1. 回顾了多项研究中高血压患者的5年生存率,以证明年龄增长、男性、未治疗时血压较高以及严重视网膜病变的不良影响。

  2. 随着舒张压升高生存率的下降并非呈线性,舒张压低于90 mmHg时死亡率相对稳定。

  3. 严重视网膜病变的不良影响与未治疗时的血压无关。

  4. 在轻度高血压患者中,即使未经治疗,5年生存率也可超过97%。

  5. 由于缺乏合适的数据,我们无法得出20世纪70年代治疗在延长寿命方面比前几十年更有效的结论。

  6. 在美国,高血压非白人患者的情况比白人患者更糟。

  7. 在接受治疗的高血压患者中,血清胆固醇与死亡率无正相关。

  8. 接受治疗的吸烟高血压患者的死亡率比不吸烟的患者至少高出两倍。

  9. 50岁以下接受治疗的患者死亡率比普通人群高出四倍。这比在老年人中观察到的任何额外死亡率都要高。

相似文献

1
Prognosis of treated hypertension 1951-1981.1951 - 1981年接受治疗的高血压患者的预后
Br J Clin Pharmacol. 1982 Jan;13(1):73-9. doi: 10.1111/j.1365-2125.1982.tb01340.x.

引用本文的文献

3
Retinal changes in malignant hypertension.恶性高血压的视网膜改变
Br Med J (Clin Res Ed). 1986 Jan 25;292(6515):233-4. doi: 10.1136/bmj.292.6515.233.

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4
Some aspects of prognosis in treated hypertension.经治疗高血压的预后的某些方面。
Br Med J. 1959 May 30;1(5134):1368-73. doi: 10.1136/bmj.1.5134.1368.
6
The natural history and course of hypertension with papilledema (malignant hypertension).
Am Heart J. 1953 Mar;45(3):331-62. doi: 10.1016/0002-8703(53)90147-1.

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