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儿童期头皮接受中等剂量X线辐射治疗后的长期脑功能变化:一项脑电图功率谱研究

Long-lasting cerebral functional changes following moderate dose x-radiation treatment to the scalp in childhood: an electroencephalographic power spectral study.

作者信息

Yaar I, Ron E, Modan B, Rinott Y, Yaar M, Modan M

出版信息

J Neurol Neurosurg Psychiatry. 1982 Feb;45(2):166-9. doi: 10.1136/jnnp.45.2.166.

Abstract

EEG tracings were compared in 44 young adults who received scalp x-radiation treatment for tinea capitis during childhood and 59 non-irradiated control subjects. The irradiated subjects were exposed, over 20 years previously, to a mean dose of 130 rads to the brain. Visual analysis of the EEG revealed an insignificant excess of abnormalities among the irradiated subjects compared to the controls. Power spectral density function analysis showed increased power values among the irradiated subjects, particularly in the beta wave frequencies. This finding provides further evidence for suspecting that x-irradiation during brain maturation may cause long-lasting damage to the brain tissue.

摘要

对44名在儿童期接受头皮X线放射治疗的头癣年轻成年人以及59名未接受照射的对照受试者的脑电图描记进行了比较。这些接受过照射的受试者在20多年前大脑平均接受了130拉德的剂量。脑电图的视觉分析显示,与对照组相比,接受照射的受试者中异常情况仅略有增加。功率谱密度函数分析表明,接受照射的受试者中功率值增加,尤其是在β波频率中。这一发现为怀疑大脑发育期间的X线照射可能对脑组织造成持久损伤提供了进一步的证据。

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本文引用的文献

1
LOW DOSE RADIATION OF THE DEVELOPING BRAIN.
Science. 1963 Sep 6;141(3584):903-5. doi: 10.1126/science.141.3584.903.
4
The late effects of tantalum 182 radiation on the cerebral cortex of monkeys.钽182辐射对猴子大脑皮层的远期效应。
J Neuropathol Exp Neurol. 1958 Jan;17(1):151-7. doi: 10.1097/00005072-195801000-00007.
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