人破伤风球蛋白的治疗效果——100例临床研究
Therapeutic efficacy of human anti-tetanic globulin--a clinical study of 100 cases.
作者信息
Bagree M M, Singh J D, Kanwar D L, Nagar R C
出版信息
Jpn J Surg. 1982;12(1):26-9. doi: 10.1007/BF02469011.
The present study was performed to evaluate clinically the therapeutic efficacy of human anti-tetanic globulin in established cases of tetanus. The study was conducted in 100 patients in India with tetanus receiving treatment at P.B.M. Hospital, Bikaner. The human anti-tetanic globulin was given in addition to equine anti-tetanic serum, to all those patients who could afford to purchase the same, irrespective of age, sex or the severity of the disease, during the period of study. Except for the administration of human anti-tetanic globulin, the management of all the patients was identical. The study revealed that human anti-tetanic globulin is effective for patients with a short period of onset. Patients having prolonged spasms at frequent intervals were also the beneficiaries, to some extent. The hospitalization period of all the patients receiving human anti-tetanic globulin was shortened.
本研究旨在临床评估人抗破伤风球蛋白对已确诊破伤风病例的治疗效果。该研究在印度比卡内尔市P.B.M.医院接受治疗的100例破伤风患者中进行。在研究期间，除了给马抗破伤风血清外，还给所有能够购买人抗破伤风球蛋白的患者使用了该药物，无论其年龄、性别或疾病严重程度如何。除了使用人抗破伤风球蛋白外，所有患者的治疗管理都是相同的。研究表明，人抗破伤风球蛋白对发病时间短的患者有效。频繁出现长时间痉挛的患者在一定程度上也是受益者。所有接受人抗破伤风球蛋白治疗的患者的住院时间都缩短了。
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