Gozariu L, Duncea I, Florescu O, Popescu E, Dumitru E, Dascălu R
Endocrinologie. 1982 Jan-Mar;20(1):43-8.
The level of circulatory calcitonin was determined by the RIA method in 45 hyperthyroid patients in evolution, before and after calcium stimulation or after pentagastrin injection. The basal calcitonin secretion was increased in only 7 of the 45 patients studied, exceeding 500 pg/ml. After a slow calcium loading the mean of calcitonin increased, but with variable individual values. The rapid calcium loading was not followed by significant increases after 30 minutes. After pentagastrin a secretory peak of over 1,800 pg/ml was obtained in 4/5 cases. Results point out the state of the calcitonin-secreting system in hyperthyroidism and its possible role in the skeleton protection in these patients.
采用放射免疫分析法（RIA）测定了45例处于病情进展期的甲亢患者在钙刺激前后或注射五肽胃泌素前后循环降钙素的水平。在研究的45例患者中，仅7例基础降钙素分泌增加，超过500 pg/ml。缓慢补钙后，降钙素平均值升高，但个体值存在差异。快速补钙30分钟后，降钙素未出现显著升高。注射五肽胃泌素后，4/5的病例出现了超过1800 pg/ml的分泌高峰。结果指出了甲亢患者降钙素分泌系统的状态及其在这些患者骨骼保护中的可能作用。
