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用吲哚菁绿评估肝血流量:连续输注法与单次注射法的比较

The estimation of hepatic blood flow with indocyanine green: comparison between the continuous infusion and single injection methods.

作者信息

Villeneuve J P, Huot R, Marleau D, Huet P M

出版信息

Am J Gastroenterol. 1982 Apr;77(4):233-7.

PMID:7072694
Abstract

We compared the estimation of hepatic blood flow obtained using a continuous infusion of indocyanine green with that obtained after a single intravenous injection of indocyanine green in 35 patients with liver disease. There was no significant difference in the values of hepatic blood flow measured by these two methods, and there was a close correlation between the continuous infusion and single injection methods (r = 0.926, p less than 0.001). In a second group of nine patients with cirrhosis, we evaluated the effect of sampling from the right versus left hepatic vein on hepatic blood flow estimation. There was no significant difference between the two estimates and a good correlation was found (r = 0.878, p less than 0.001). Since values of hepatic blood flow measured after a single indocyanine green injection are similar to those measured using the more classical continuous infusion method, the single injection method may be preferable since it requires only 15 min to be performed.

摘要

我们比较了35例肝病患者中,通过连续输注吲哚菁绿和单次静脉注射吲哚菁绿所获得的肝血流量估计值。这两种方法测得的肝血流量值无显著差异,连续输注法和单次注射法之间存在密切相关性(r = 0.926,p < 0.001)。在第二组9例肝硬化患者中,我们评估了从右肝静脉与左肝静脉采样对肝血流量估计的影响。两种估计值之间无显著差异,且相关性良好(r = 0.878,p < 0.001)。由于单次注射吲哚菁绿后测得的肝血流量值与使用更经典的连续输注法测得的值相似,单次注射法可能更可取,因为它只需15分钟即可完成。

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1
The estimation of hepatic blood flow with indocyanine green: comparison between the continuous infusion and single injection methods.用吲哚菁绿评估肝血流量:连续输注法与单次注射法的比较
Am J Gastroenterol. 1982 Apr;77(4):233-7.
2
Determination of hepatic blood flow in the rat using sequential infusions of indocyanine green or galactose.使用吲哚菁绿或半乳糖连续输注法测定大鼠肝血流量。
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Functional and non-functional liver blood flow in patients with liver cirrhosis measured by indocyanine green.通过吲哚菁绿测量肝硬化患者的功能性和非功能性肝血流。
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Plasma elimination of indocyanine green in the intact pig after bolus injection and during constant infusion: comparison of spectrophotometry and high-pressure liquid chromatography for concentration analysis.静脉推注和持续输注后完整猪体内吲哚菁绿的血浆清除:分光光度法和高压液相色谱法用于浓度分析的比较
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Simultaneous measurement of effective hepatic blood flow and systemic circulation.有效肝血流量与体循环的同步测量。
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[Determination of hepatic blood flow in chronic liver diseases using the constant infusion technic].
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[Hepatic extraction of taurocholate and indocyanine green in patients with liver disease (author's transl)].
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Effect of liver blood flow and function on hepatic indocyanine green clearance measured directly in a cirrhotic animal model.肝血流和功能对肝硬化动物模型中直接测量的肝脏吲哚菁绿清除率的影响。
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Assessment of hepatic blood flow in healthy subjects by continuous infusion of indocyanine green.通过持续输注吲哚菁绿评估健康受试者的肝血流量。
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Hepatic drug clearance: the effect of age using indocyanine green as a model compound.肝脏药物清除率:以吲哚菁绿为模型化合物研究年龄的影响。
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