Villeneuve J P, Huot R, Marleau D, Huet P M
Am J Gastroenterol. 1982 Apr;77(4):233-7.
We compared the estimation of hepatic blood flow obtained using a continuous infusion of indocyanine green with that obtained after a single intravenous injection of indocyanine green in 35 patients with liver disease. There was no significant difference in the values of hepatic blood flow measured by these two methods, and there was a close correlation between the continuous infusion and single injection methods (r = 0.926, p less than 0.001). In a second group of nine patients with cirrhosis, we evaluated the effect of sampling from the right versus left hepatic vein on hepatic blood flow estimation. There was no significant difference between the two estimates and a good correlation was found (r = 0.878, p less than 0.001). Since values of hepatic blood flow measured after a single indocyanine green injection are similar to those measured using the more classical continuous infusion method, the single injection method may be preferable since it requires only 15 min to be performed.
我们比较了35例肝病患者中,通过连续输注吲哚菁绿和单次静脉注射吲哚菁绿所获得的肝血流量估计值。这两种方法测得的肝血流量值无显著差异,连续输注法和单次注射法之间存在密切相关性(r = 0.926,p < 0.001)。在第二组9例肝硬化患者中,我们评估了从右肝静脉与左肝静脉采样对肝血流量估计的影响。两种估计值之间无显著差异,且相关性良好(r = 0.878,p < 0.001)。由于单次注射吲哚菁绿后测得的肝血流量值与使用更经典的连续输注法测得的值相似,单次注射法可能更可取,因为它只需15分钟即可完成。