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Complement-mediated adherence of cells to microfilariae of Brugia malayi.

作者信息

Piessens W F, da Silva W D

出版信息

Am J Trop Med Hyg. 1982 Mar;31(2):297-301. doi: 10.4269/ajtmh.1982.31.297.

DOI:10.4269/ajtmh.1982.31.297
PMID:7072893
Abstract

Immune sera promote the adherence of human buffy coat cells to microfilariae of Brugia malayi. This effect is augmented by the simultaneous addition of fresh human or guinea pig serum. The heat-labile, adherence-promoting factor present in nonimmune sera appears to be complement. In the absence of antibody, microfilariae activate complement via the alternative pathway and C3 is deposited on the microfilarial sheath.

摘要

相似文献

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Am J Trop Med Hyg. 1982 Mar;31(2):297-301. doi: 10.4269/ajtmh.1982.31.297.
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