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新生儿寻常型天疱疮:被动转移的天疱疮抗体的作用

Neonatal pemphigus vulgaris: role of passively transferred pemphigus antibodies.

作者信息

Moncada B, Kettelsen S, Hernández-Moctezuma J L, Ramirez F

出版信息

Br J Dermatol. 1982 Apr;106(4):465-7. doi: 10.1111/j.1365-2133.1982.tb04542.x.

DOI:10.1111/j.1365-2133.1982.tb04542.x
PMID:7073971
Abstract

A neonate with oral lesions of pemphigus vulgaris is described. The diagnosis was confirmed by cytological examination of lesions, positive intercellular IgG staining of the acantholytic cells, and presence of pemphigus antibodies in his serum. At the time of delivery, the child's mother had active pemphigus vulgaris, and it is suggested that this was a case of passively transferred disease.

摘要

本文描述了一名患有寻常型天疱疮口腔损害的新生儿。通过对损害进行细胞学检查、棘层松解细胞的细胞间IgG染色阳性以及患儿血清中存在天疱疮抗体,确诊了该病。患儿分娩时,其母亲患有活动性寻常型天疱疮,提示这是一例被动转移疾病的病例。

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The long and the short of it: insights into the cellular source of autoantibodies as revealed by B cell depletion therapy.
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