Hooper R R, Reynolds G H, Jones O G, Zaidi A, Wiesner P J, Latimer K P, Lester A, Campbell A F, Harrison W O, Karney W W, Holmes K K
Am J Epidemiol. 1978 Aug;108(2):136-44. doi: 10.1093/oxfordjournals.aje.a112597.
Reliable data on the risk of transmission of N. gonorrhoeae would enhance our understanding of the importance of host defenses against gonorrhea and would aid in the evaluation of prophylactic measures. This paper examines the risk of transmission of gonorrhea from infected female to male and the role that variables such as race, prophylaxis and amount of exposure play in the development of gonococcal urethritis. Volunteer crew members of a large naval vessel were followed prospectively as a cohort to study their risk of acquiring gonococcal infection during a four-day liberty period in the Far East. At the same time the prevalence of N. gonorrhoeae was determined in a population of females to whom the sailors were exposed. The calculated risk of transmission per exposure with an infected partner was .19 for whites and .53 for blacks. A statistically significant relationship was noted between the risk of transmission of gonorrhea and both the number of partners and the frequency of sexual intercourse. Further, the increasing infection rate with increasing numbers of exposures in men who had a single sex partner suggests that the majority of men are in fact susceptible to gonorrhea if the quantity of exposure is sufficient.
关于淋病奈瑟菌传播风险的可靠数据将增进我们对宿主防御淋病重要性的理解，并有助于评估预防措施。本文研究了淋病从受感染女性传播至男性的风险，以及种族、预防措施和接触量等变量在淋菌性尿道炎发病过程中所起的作用。一艘大型海军舰艇的志愿船员作为一个队列被前瞻性地跟踪，以研究他们在远东地区为期四天的休假期间感染淋球菌的风险。与此同时，确定了水手们接触的女性群体中淋病奈瑟菌的流行情况。与受感染伴侣每次接触的计算传播风险，白人是0.19，黑人是0.53。淋病传播风险与性伴侣数量和性交频率之间存在统计学上的显著关系。此外，在只有单一性伴侣的男性中，随着接触次数增加感染率上升，这表明如果接触量足够，实际上大多数男性都易感染淋病。
