来自小肠结肠炎耶尔森氏菌O3对鼠疫耶尔森氏菌的温度调节免疫原性。
Temperature-modulated immunogenicity to Yersinia pestis from Yersinia enterocolitica O3.
作者信息
Alonso J M, Hurtrel B, Mazigh D, Chalvignac M A, Mollaret H H
出版信息
Infect Immun. 1982 Apr;36(1):423-5. doi: 10.1128/iai.36.1.423-425.1982.
Abstract
The ability of Yersinia enterocolitica O3, grown at 25 degrees C, to promote cross-immunity to Y. pestis was lost after repeated subcultures at 37 degrees C, which selected for bacterial populations having lower in vivo survival. Subculturing Y. enterocolitica O3 from 37 to 25 degrees C restored the cross-immunogenicity although the in vivo survival remained low.
摘要
在25摄氏度下生长的小肠结肠炎耶尔森菌O3菌株促进对鼠疫耶尔森菌产生交叉免疫的能力，在37摄氏度下反复传代培养后丧失，因为这种传代培养筛选出了体内存活率较低的细菌群体。将小肠结肠炎耶尔森菌O3从37摄氏度传代培养至25摄氏度可恢复交叉免疫原性，尽管其体内存活率仍然较低。
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