Lim P L, Rowley D
Int Arch Allergy Appl Immunol. 1982;68(1):41-6. doi: 10.1159/000233065.
Oral immunization was shown to reduce the passage of bacterial antigen (BA) through the intestinal wall. The extent of the reduction found was dependent on the technique used for antigen assay, but with 125I-BA in an everted gut sac system, the amount of transported antigen was less than 60% of the amount in a control non-immune system. The inhibitory effect was due to coproantibodies which probably function by complexing and trapping the antigen in the mucous layer. This inhibition of antigen transport seems a prerogative of IgA antibodies since serum-derived antibodies caused concomitant adverse effects.
口服免疫可减少细菌抗原（BA）通过肠壁的量。所发现的减少程度取决于用于抗原检测的技术，但在翻转型肠囊系统中使用125I-BA时，转运抗原的量不到对照非免疫系统中抗原量的60%。这种抑制作用是由于粪抗体，其可能通过在粘液层中使抗原形成复合物并捕获抗原来发挥作用。抗原转运的这种抑制似乎是IgA抗体的特性，因为血清来源的抗体可引起相应的不良反应。
